Table 7 ROC cutoff analysis for histamine, DAO and chymase between the groups
Molecule | Groups | Cutoff | Sensitivity | Specificity | PPV | NPV | AUC | AUC labeling |
|---|---|---|---|---|---|---|---|---|
Histamine (ng/ml) | Control vs. Chewers | 1.091 | 100% | 0% | 50% | NA | 0.178 | Poor |
Control vs. OSMF | 1.58 | 100% | 100% | 100% | 100% | 1 | Excellent | |
Chewers vs. OSMF | 1.12 | 92.31% | 100% | 100% | 92.86% | 0.994 | Excellent | |
DAO (ng/ml) | Control vs. Chewers | 0.259 | 53.85% | 84.62% | 77.88% | 64.71 | 0.707 | Moderate |
Control vs. OSMF | 0.084 | 84.62% | 23.08% | 52.38% | 60% | 0.364 | Poor | |
Chewers vs. OSMF | 0.556 | 38.46% | 100% | 100% | 61.9% | 0.615 | Moderate | |
Chymase (pg/ml) | Control vs. Chewers | 22.32 | 92.31% | 23.08% | 54.55% | 75% | 0.334 | Poor |
Control vs. OSMF | 14.19 | 100% | 0% | 50% | NA | 0.00 | Poor | |
Chewers vs. OSMF | 19.45 | 100% | 0% | 50% | NA | 0.00 | Poor |