Fig. 4

Change in bone turnover markers between conservative and surgical groups at the initial examination and MRONJ resolution (blue column, initial examination; orange column, MRONJ resolution). *p < 0.05. CTX, C-telopeptide of type I collagen (ng/mL); OC, osteocalcin(ng/mL); P1NP, procollagen type 1 N-terminal propeptide (ng/mL); 25(OH)D, 25-hydroxyvitamin D (ng/mL); PTH, parathyroid hormone (pg/mL); Ca, calcium (mg/dL); P, inorganic P (mg/dL); MRONJ, medication-related osteonecrosis of the jaw