From: Recurrent aphthous stomatitis (RAS) and its related factors among the Azar cohort population
Variables | Categories | Unadjusted | Adjusted | ||||
---|---|---|---|---|---|---|---|
OR1 | 95% CI2 | p-value | OR | 95% CI | p-value | ||
Gender | Female | 1.33 | 1.23–1.44 | < 0.001 | 1.05 | 0.94–1.16 | 0.39 |
Male | Ref | ||||||
Age (years) | ≥ 50 | 0.63 | 0.59–0.69 | < 0.001 | 0.78 | 0.71–0.86 | < 0.001 |
< 50 | Ref | ||||||
Wealth Scale Index | Very Poor | 0.68 | 0.60–0.76 | < 0.001 | 0.74 | 0.65–0.84 | < 0.001 |
Poor | 0.76 | 0.76–0.86 | < 0.001 | 0.85 | 0.74–0.97 | 0.02 | |
Moderate | 0.85 | 0.75–0.96 | 0.007 | 0.89 | 0.79–1.01 | 0.08 | |
Good | 0.99 | 0.89–1.12 | 0.93 | 0.95 | 0.84–1.07 | 0.42 | |
Very Good | Ref | ||||||
Educational level | Under diploma | 0.63 | 0.56–0.72 | < 0.001 | 0.83 | 0.71–0.96 | 0.01 |
Diploma | 0.85 | 0.74–0.97 | 0.02 | 0.95 | 0.83–1.10 | 0.50 | |
University | Ref | ||||||
Place of residence | Rural | 0.96 | 0.89–1.05 | 0.36 | - | - | - |
Urban | Ref | ||||||
Tooth brushing frequency (per day) | ≥ 1 | 0.70 | 0.64–0.76 | < 0.001 | 1.02 | 0.93–1.13 | 0.66 |
< 1 | Ref | ||||||
Smoking | Never | Ref | |||||
Ex-smoker | 0.69 | 0.59–0.80 | < 0.001 | 0.79 | 0.67–0.93 | 0.01 | |
Smoker | 0.51 | 0.45–0.58 | < 0.001 | 0.55 | 0.47–0.63 | < 0.001 | |
Alcohol Consumption | Yes | 0.65 | 0.47–0.89 | 0.007 | 0.89 | 0.64–1.25 | 0.50 |
No | Ref | ||||||
Genital Aphthous | Yes | 29.73 | 16.73–52.84 | < 0.001 | 28.93 | 16.18–51.72 | < 0.001 |
No | Ref | ||||||
Hypertension | Yes | 0.81 | 0.74–0.90 | < 0.001 | 0.91 | 0.82–1.02 | 0.10 |
No | Ref | ||||||
Diabetes | Yes | 0.79 | 0.70–0.90 | < 0.001 | 0.90 | 0.79–1.03 | 0.11 |
No | Ref | ||||||
Depression | Yes | 1.43 | 1.30–1.58 | < 0.001 | 1.36 | 1.22–1.51 | < 0.001 |
No | Ref | ||||||
Rheumatic Disease | Yes | 1.38 | 1.14–1.68 | 0.001 | 1.30 | 1.06–1.59 | 0.01 |
No | Ref | ||||||
Chronic Headaches | Yes | 1.14 | 1.02–1.27 | 0.02 | 0.94 | 0.84–1.06 | 0.34 |
No | Ref | ||||||
Chronic Lung Disease | Yes | 1.21 | 1.00-1.47 | 0.06 | 1.21 | 0.99–1.48 | 0.67 |
No | Ref | ||||||
Thyroid Disease | Yes | 1.18 | 1.04–1.35 | 0.01 | 1.00 | 0.87–1.15 | 0.98 |
No | Ref | ||||||
Anemia | Yes | 1.11 | 0.94–1.30 | 0.23 | - | - | - |
No | Ref | ||||||
Multiple sclerosis | Yes | 1.64 | 0.66–4.07 | 0.28 | - | - | - |
No | Ref | ||||||
Epilepsy | Yes | 1.04 | 0.69–1.56 | 0.85 | - | - | - |
No | Ref | ||||||
Folic acid supplement | Yes | 1.45 | 1.09–1.93 | 0.01 | 1.02 | 0.75–1.39 | 0.89 |
No | Ref | ||||||
Iron supplement | Yes | 1.45 | 1.20–1.75 | < 0.001 | 1.14 | 0.94–1.39 | 0.19 |
No | Ref | ||||||
Vitamin D (Tablet) supplement | Yes | 1.29 | 0.94–1.76 | 0.12 | 1.06 | 0.77–1.48 | 0.71 |
No | Ref | ||||||
Vitamin D (injection) supplement | Yes | 1.63 | 1.10–2.41 | 0.02 | 0.32 | 0.88–1.98 | 0.18 |
No | Ref | ||||||
Zinc supplement | Yes | 1.31 | 1.06–1.62 | 0.01 | 1.18 | 0.94–1.48 | 0.15 |
No | Ref | ||||||
Multi-vitamine supplement | Yes | 1.20 | 0.79–1.83 | 0.39 | - | - | - |
No | Ref | ||||||
Food Allergy | Yes | 1.39 | 1.24–1.55 | < 0.001 | 1.24 | 1.10–1.40 | < 0.001 |
No | Ref | ||||||
Body mass index (kg/m2) | < 18.5 | 0.92 | 0.56–1.51 | 0.74 | 1.16 | 0.70–1.94 | 0.57 |
25-29.9 | 1.07 | 0.97–1.19 | 0.18 | 1.00 | 0.90–1.11 | 0.95 | |
30≥ | 0.97 | 0.88–1.08 | 0.58 | 0.88 | 0.79–0.99 | 0.03 | |
18.5–24.9 | Ref | ||||||
DMFT3 | - | 0.98 | 0.97–0.98 | < 0.001 | 0.99 | 0.98–0.99 | < 0.001 |