Table 3 The mediation effect of educational attainment on chronic periodontitis via household income and cigarettes smoked per day
From: Mediators of the association between education and periodontitis: Mendelian randomization study
Mediator | Total effect | Direct effect 1 | Direct effect 2 | Mediation effect | Â | Mediated proportion (%) (95% CI) |
|---|---|---|---|---|---|---|
β (95% CI) | β (95% CI) | β (95% CI) | β (95% CI) | P | ||
BMI | -0.33(0.47,-0.20) | -0.23(-0.28,-0.18) | 0.19(0.02,0.36) | -0.04(-0.06,-0.03) | 3.46*10− 9 | 12.9(8.6,17.2) |
Cigarettes smoked per day | -0.33(0.47,-0.20) | -0.35(-0.40,-0.30) | 0.29(0.13,0.46) | -0.10(-0.13, -0.08) | 1.32*10− 17 | 30.7(23.7,37.8) |
Household income | -0.33(0.47,-0.20) | 0.66(0.64,0.68) | -0.46(-0.86,-0.05) | -0.30(-0.32, -0.28) | 8.39*10− 268 | 89.9(84.8,94.9) |
Alcoholic drinks per week | -0.33(0.47,-0.20) | 0.04(0.02,0.06) | 0.74(0.18,1.29) | 0.03(0.02, 0.05) | 8.26*10− 6 | 9.7(5.5,14.0) |
Major depression | -0.33(0.47,-0.20) | -0.24(-0.28,-0.19) | 0.23(0.02,0.44) | -0.05(-0.07, -0.04) | 3.65*10− 12 | 16.4(11.8,21.1) |