Fig. 7

An in vitro transwell migration model was set up to analyze the ability of sEVs to induce site-directed migration of DPCs. A, B, C & D are inverted light microscope images showing the potentiality of control (A), 0.2 mg/mL MTA (B), 50 µg/mL sEVs (C) and the combination of 0.2 mg/mL MTA and 50 µg/mL sEVs (D) on DPCs migration (x10). (E) Bar graph representing % of migrated DPCs of transwell migration assay Statistical comparisons to the control group are labeled with # symbols: ## p <.01,### p <.001. Comparisons between treatment groups are indicated by * symbols: * p <.05, ** p <.01, *** p <.001