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Table 2 Comparison of peripheral blood biomarker levels in different oral mucosal lesions

From: Application of machine learning for the analysis of peripheral blood biomarkers in oral mucosal diseases: a cross-sectional study

indexes

health(n = 82)

RAU(n = 100)

OLP(n = 35)

AG(n = 67)

BMS(n = 35)

F

P

humoral immune indexes

IgG(g/L)

12.07 ± 2.48b

14.82 ± 14.37a

12.67 ± 2.30

12.51 ± 2.50

12.53 ± 1.73

1.536

0.191

IgA(g/L)

2.44 ± 0.94

2.63 ± 1.07

2.57 ± 0.99

2.35 ± 0.89

2.49 ± 0.79

1.008

0.403

IgM(g/L)

1.06 ± 0.44

1.17 ± 0.56

1.15 ± 0.48

1.11 ± 0.52

1.03 ± 0.47

0.757

0.554

C3(g/L)

1.18 ± 0.21

1.16 ± 0.22

1.16 ± 0.19

1.14 ± 0.173

1.16 ± 0.24

0.383

0.821

C4(g/L)

0.28 ±.085d

0.30 ± 0.10

0.28 ± 0.10

0.31 ± 0.11ae

0.27 ± 0.08d

2.042

0.088

vitamin B content

VB1(ng/ml)

2.13 ± 1.35

2.09 ± 1.25

2.10 ± 1.18

2.68 ± 3.00

2.06 ± 1.23

1.412

0.23

VB2(ng/ml)

6.58 ± 4.38bd

13.29 ± 16.34a

9.56 ± 7.66

11.47 ± 15.01a

10.54 ± 9.60

3.481

0.008*

VB3(ng/ml)

18.83 ± 8.70b

26.24 ± 21.28ace

19.92 ± 11.01b

23.70 ± 15.31

19.84 ± 13.58b

3.135

0.015*

VB5(ng/ml)

34.27 ± 19.19cd

32.39 ± 19.52c

25.32 ± 9.38ab

28.07 ± 10.27a

28.11 ± 9.14

2.972

0.02*

micronutrient levels

Serum Zn(µmol/L)

14.55 ± 1.74bcde

12.84 ± 2.70a

13.15 ± 2.60a

13.46 ± 2.21a

12.82 ± 1.85a

7.405

< 0.001*

Serum Fe(µmol/L)

19.62 ± 4.70bcde

14.44 ± 5.55a

16.32 ± 6.12a

16.44 ± 7.59a

15.37 ± 4.83a

9.301

< 0.001*

UIBC(µmol/L)

40.48 ± 7.17

42.18 ± 11.95d

38.35 ± 9.66

38.19 ± 10.66b

38.85 ± 9.08

2.102

0.08

TIBC(µmol/L)

60.10 ± 6.33bcde

56.61 ± 9.52a

54.67 ± 7.75a

54.18 ± 7.49a

54.22 ± 7.34a

6.82

< 0.001*

iron saturation(%)

32.84 ± 7.84b

26.37 ± 11.01ad

30.17 ± 11.57

30.13 ± 13.44b

28.77 ± 9.83

4.181

0.003*

  1. Note: After the Normality test and homogeneity of variance test, the measurement data of each group were consistent with normal distribution. T-test was used for comparison of the two groups, one-way ANOVA was used for comparison among multiple groups, and LDS test was used for comparison between two groups. aP < 0.05 compared with the healthy group, bP < 0.05 compared with the RAU group, cP < 0.05 compared with the OLP group, dP < 0.05 compared with the AG group, eP < 0.05 compared with the BMS group, *p < 0.05